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Fabrication and Functionalisation of Nanocarbon-Based Field-Effect Transistor Biosensors.

Chang-Seuk LeeRebecca E A GwytherMark FreeleyD Dafydd JonesMatteo Palma
Published in: Chembiochem : a European journal of chemical biology (2022)
Nanocarbon-based field-effect transistor (NC-FET) biosensors are at the forefront of future diagnostic technology. By integrating biological molecules with electrically conducting carbon-based platforms, high sensitivity real-time multiplexed sensing is possible. Combined with their small footprint, portability, ease of use, and label-free sensing mechanisms, NC-FETs are prime candidates for the rapidly expanding areas of point-of-care testing, environmental monitoring and biosensing as a whole. In this review we provide an overview of the basic operational mechanisms behind NC-FETs, synthesis and fabrication of FET devices, and developments in functionalisation strategies for biosensing applications.
Keyphrases
  • label free
  • low cost
  • tissue engineering
  • current status
  • single cell
  • human health
  • risk assessment
  • life cycle