Nitrergic signaling via interstitial cells of Cajal and smooth muscle cells influences circular smooth muscle contractility in murine colon.

K BeckAndreas Friebe Barbara Voussen

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)

We conclude that short rings of murine colon can be effectively used to record spontaneous contractions. Although NO-GC in SMC determines smooth muscle tone, concerted action of NO-GC in both SMC and ICC modulates slow phasic contractions and large contractions.

Keyphrases

smooth muscle
induced apoptosis
gas chromatography
endoplasmic reticulum stress
oxidative stress
cell proliferation
tandem mass spectrometry
solid phase extraction