The Efficacy of High-Dose Pulse Therapy vs. Low-Dose Intravenous Methylprednisolone on Severe to Critical COVID-19 Clinical Outcomes: A Randomized Clinical Trial.
Zahra SahraeiParnaz PanahiKouroush SolhjoukhahMaryam MesbahSiamak AfaghiMahdi AmirdosaraJamshid SalamzadehFarzad Esmaeili TarkiIlad Alavi DarazamPublished in: Iranian journal of pharmaceutical research : IJPR (2023)
The use of adjuvant pulse therapy with intravenous methylprednisolone did not result in improved in-hospital clinical outcomes among patients with mild to moderate ARDS due to COVID-19. A higher risk of bacterial pneumonia should be considered in such cases as receiving a higher dose of steroids.
Keyphrases
- high dose
- low dose
- coronavirus disease
- stem cell transplantation
- sars cov
- blood pressure
- healthcare
- early stage
- early onset
- acute respiratory distress syndrome
- stem cells
- emergency department
- mesenchymal stem cells
- mechanical ventilation
- adverse drug
- cell therapy
- electronic health record
- intensive care unit
- acute care