Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.
Zhixiang HuLiangqing DongShengli LiZhe LiYejun QiaoYuchen LiJie DingZhiao ChenYangjun WuZhen WangShenglin HuangQiang GaoYingjun ZhaoXiang-Huo HePublished in: Hepatology (Baltimore, Md.) (2020)
Taken together, our findings identify the DHX9-NONO-SFPQ complex as a key regulator manipulating the oncogenic splicing switch of BIN1 and as a candidate therapeutic target in liver cancer.