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Drug susceptibility profiles and factors associated with non-tuberculous mycobacteria species circulating among patients diagnosed with pulmonary tuberculosis in Tanzania.

Togolani Godfrey MayaErick Vitus KombaGloria Ivy MensahPeter Masunga MbeleleStella George MpagamaSayoki Godfrey MfinangaKennedy Kwasi AddoRudovick Reuben Kazwala
Published in: PloS one (2022)
In this study, MAC was the most frequently isolated NTM species followed by MABC. While all MAC and MABC identified, were susceptible to aminoglycosides, three MABC were resistant to the macrolides due to mutation at position 28 of the erm (41) gene. For this, it is important for clinicians need to rule out NTM, understand species and their drug susceptibility for optimal case management.
Keyphrases
  • pulmonary tuberculosis
  • mycobacterium tuberculosis
  • genetic diversity
  • palliative care
  • genome wide
  • emergency department
  • copy number
  • drug induced