Association Between Types of Carbapenemase and Clinical Outcomes of Infection Due to Carbapenem Resistance Enterobacterales.
Korawan PudpongSutthiporn PattharachayakulWichai SantimaleeworagunSupayang Piyawan VoravuthikunchaiVaraporn LaohaprertthisanThanaporn HortiwakulBoonsri CharernmakSarunyou ChusriPublished in: Infection and drug resistance (2022)
Our findings suggest that the mortality for CP-CRE infection in patients with NDM-1 or NDM-1/OXA-48 was higher than the mortality in those with OXA-48, which It seems that the type of carbapenemase gene may affect meropenem MIC levels. Hence, in treatment decisions involving the use of either carbapenem-containing regiment or colistin-containing regiment in patients with CP-CRE infection, especially those in the NDM-1 and NDM-1/OXA-48 groups, the patient symptoms should be closely monitored.
Keyphrases
- klebsiella pneumoniae
- multidrug resistant
- escherichia coli
- acinetobacter baumannii
- gram negative
- cardiovascular events
- drug resistant
- risk factors
- genome wide
- cardiovascular disease
- case report
- type diabetes
- gene expression
- pseudomonas aeruginosa
- depressive symptoms
- cystic fibrosis
- dna methylation
- transcription factor
- replacement therapy