Comparing the impact of genotypic based diagnostic algorithm on time to treatment initiation and treatment outcomes among drug-resistant tuberculosis patients in Amhara region, Ethiopia.

Getahun Molla Kassa Mehari Woldemariam MeridAtalay Goshu MulunehHaileab Fekadu Wolde

Published in: PloS one (2021)

Xpert MTB/RIF can mitigate the transmission of DR-TB significantly via quick diagnosis and treatment initiation followed by LPA as equating to the solid culture base DST, particularly in smear-positive patients. However, we didn't see a statistically significant impact in terms of treatment outcomes. Xpert MTB/RIF can be used as the first test to diagnose DR-TB by further complimenting solid culture base DST to grasp the drug-resistance profile.

Keyphrases

pulmonary tuberculosis
mycobacterium tuberculosis
drug resistant
end stage renal disease
ejection fraction
peritoneal dialysis
multidrug resistant
prognostic factors
machine learning
emergency department
hiv aids
editorial comment
replacement therapy