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A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk.

Maria Jose RedondoSusan GeyerAndrea K SteckSeth SharpJohn M WentworthMichael N WeedonPeter AntinozziJay M SosenkoMark AtkinsonAlberto PuglieseRichard A Oramnull null
Published in: Diabetes care (2018)
The T1D GRS independently predicts progression to T1D and improves prediction along T1D stages in autoantibody-positive relatives.
Keyphrases
  • type diabetes
  • glycemic control
  • cardiovascular disease
  • insulin resistance
  • genome wide
  • gene expression
  • metabolic syndrome
  • copy number
  • dna methylation
  • skeletal muscle
  • adipose tissue
  • weight loss
  • celiac disease