Allogeneic CD34-selected stem cell boost as salvage treatment of life-threatening infection and severe cytopenias after CAR-T cell therapy.

Pablo Silva de TenaRebeca Bailen AlmoroxGillen OarbeascoaIgnacio Gómez-CenturiónAna Pérez-CorralDiego CarbonellCarolina Martínez-LapercheMilagros SanchoMariana Bastos-OreiroDiego Conde-RoyoPaula Fernández-CaldasCristina MuñozSantiago SabellIsmael BuñoJavier AnguitaJosé Luis Díez-MartínMi Kwon

Published in: Transfusion (2022)

This case illustrates as proof-of-concept the efficacy and safety of selected CD34-stem cell boost from prior donor as salvage treatment of prolonged cytopenias after CAR-T cell therapy.

Keyphrases

cell therapy
stem cells
mesenchymal stem cells
stem cell transplantation
bone marrow
combination therapy
early onset
low dose
high dose
nk cells
smoking cessation
drug induced