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Embryonal tumor with multilayered rosettes: a report of a rare case.

Sultan A AlshoabiAli M AbduHisham M AlkhalidiMiral D JhaveriAbdullgabbar M Hamid
Published in: BJR case reports (2022)
The authors report a case of an embryonal tumor with multilayered rosettes (ETMR) in an 18-month-old female infant who presented with gait imbalance and progressive left-sided weakness for 2 months. ETMR is a rare small round blue cell aggressive tumor of the central nervous system characterized by the amplification of the C19MC region on chromosome 19 (Chr19q13.42). This report in detail the clinical-radiologic and histopathological workup and diagnosis. Because ETMRs are newly described rare pediatric central nervous system tumors with only a few reported cases, we aim to document this typical case to add to the existing data on these tumors.
Keyphrases
  • rare case
  • multiple sclerosis
  • single cell
  • electronic health record
  • stem cells
  • gene expression
  • machine learning
  • bone marrow
  • mesenchymal stem cells
  • copy number
  • genome wide