Sequestosome 1 (p62) mitigates hypoxia-induced cardiac dysfunction by stabilizing hypoxia-inducible factor 1α and nuclear factor erythroid 2-related factor 2.

Rajeshwary GhoshAmir Nima FatahianOmid M T RouzbehaniMarissa A HathawayTariq MoslehVishaka VinodSidney VowlesSophie L StephensSiu-Lai Desmond ChungIsaac D CaoAnila JonnavithulaJ David SymonsSihem Boudina

Published in: Cardiovascular research (2024)

Cardiac p62 mitigates hypoxia-induced cardiac dysfunction by stabilizing Hif-1α and Nrf2.

Keyphrases

nuclear factor
left ventricular
oxidative stress
toll like receptor
heart failure
radiation induced
inflammatory response