Microbiome-Related Indole and Serotonin Metabolites are Linked to Inflammation and Psychiatric Symptoms in People Living with HIV.

Nadira VadaqYue ZhangElise MeederLisa Van de WijerMuhammad Hussein GasemLeo Ab JoostenMihai G NeteaQuirijn de MastVasiliki MatzarakiArnt SchellekensJingyuan FuAndré Jam van der Ven

Published in: International journal of tryptophan research : IJTR (2022)

Our results suggest that gut bacterial composition and dysbiosis in PLHIV on ART contribute to tryptophan metabolism, which may have clinical consequences for immune function and behavior.

Keyphrases

oxidative stress
mental health
ms ms
hiv infected
antiretroviral therapy
depressive symptoms