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SGLT-2 inhibitors and cardiovascular outcomes in patients with and without a history of heart failure: a systematic review and meta-analysis.

Victor RazukMauro ChiaritoDavide CaoJohny NicolasCarlo A PivatoAnton CamajDavid PowerFrans J BeerkensDavis JonesAviv AlterAlvin MathewAlessandro SpiritoJohanna P ContrerasGeorge D DangasRoxana Mehran
Published in: European heart journal. Cardiovascular pharmacotherapy (2022)
SGLT-2 inhibitors improved CV outcomes irrespective of heart failure history or type, and severity of LVEF reduction.
Keyphrases
  • heart failure
  • left ventricular
  • acute heart failure
  • cardiac resynchronization therapy
  • atrial fibrillation
  • type diabetes
  • adipose tissue
  • insulin resistance
  • weight loss