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Cabergoline treatment promotes myocardial recovery in peripartum cardiomyopathy.

Tobias J PfefferJulia H MuellerLea HaebelSergej ErschowKuebra C YalmanSteven R TalbotTobias KoenigDominik BerlinerCarolin ZwadloMichaela ScherrDenise Hilfiker-KleinerJohann BauersachsMelanie Ricke-Hoch
Published in: ESC heart failure (2022)
In the experimental PPCM mouse model, the selective D2R agonist cabergoline prevents the onset of postpartum HF similar to bromocriptine. In PPCM patients, cabergoline treatment was safe and effective as all patients fully recovered. Cabergoline might serve as a promising alternative to bromocriptine. However, these findings are based on experimental data and a small case series and thus have to be interpreted with caution and should be validated in a larger clinical trial.
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