Why harmonization is needed when using FDG PET/CT as a prognosticator: demonstration with EARL-compliant SUV as an independent prognostic factor in lung cancer.
Benjamin HouduCharline LasnonIdlir LicajGuy ThomasPascal DoAnne-Valerie GuizardCédric DesmontsNicolas AidePublished in: European journal of nuclear medicine and molecular imaging (2018)
The present study provides the PET community with an EARL-compliant SUVmax as an independent prognosticator for advanced NSCLC that should be confirmed in a larger cohort, ideally at other EARL accredited centres, and highlights the need to harmonize PET quantitative metrics when using them for risk stratification of patients.