Deregulation of IL-37 and its miRNAs modulators in sarcopenic patients after rehabilitation.
Francesca La RosaSimone AgostiniMarina SaresellaAndrea Saul CostaFederica PianconeRossella MiglioliFabio TrecateMario ClericiPublished in: Journal of translational medicine (2021)
Results herein confirm that successful rehabilitation for sarcopenia results in a reduction of the inflammatory milieu, raise the possibility that IL-37 may be a key target to monitor the rehabilitation-associated improvement in sarcopenia, and suggest that this cytokine could be a therapeutic target in sarcopenic patients.