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Deregulation of IL-37 and its miRNAs modulators in sarcopenic patients after rehabilitation.

Francesca La RosaSimone AgostiniMarina SaresellaAndrea Saul CostaFederica PianconeRossella MiglioliFabio TrecateMario Clerici
Published in: Journal of translational medicine (2021)
Results herein confirm that successful rehabilitation for sarcopenia results in a reduction of the inflammatory milieu, raise the possibility that IL-37 may be a key target to monitor the rehabilitation-associated improvement in sarcopenia, and suggest that this cytokine could be a therapeutic target in sarcopenic patients.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • skeletal muscle
  • small molecule
  • oxidative stress