Tumor treating fields increases blood-brain barrier permeability and relative cerebral blood volume in patients with glioblastoma.

Michael IvLewis NayaSajal SananSamuel L Van BuskirkSeema NagpalReena P ThomasLawrence D RechtChirag B Patel

Published in: The neuroradiology journal (2023)

Using pMRI, we provide initial in-human validation of pre-clinical studies regarding the effects of TTFields on tumor blood volume and BBB permeability in GBM.

Keyphrases

blood brain barrier
endothelial cells
cerebral ischemia
subarachnoid hemorrhage
induced pluripotent stem cells
cerebral blood flow
clinical evaluation