Genome-Wide Interaction Analysis With DASH Diet Score Identified Novel Loci for Systolic Blood Pressure.
Mélanie GuiretteJessie LanNicola M McKeownMichael R BrownHan-Yang ChenPaul S de VriesHyunju KimCasey M RebholzAlanna C MorrisonTraci M BartzAmanda M FrettsXiuqing GuoRozenn N LemaitreChing-Ti LiuRaymond NoordamRenée de MutsertFrits Richard RosendaalCarol A WangLawrence J BeilinTrevor A MoriWendy H OddyCraig E PennellJin Fang ChaiClare WhittonRob Martinus van DamJian-Jun LiuE-Shyong TaiXueling S SimMarian L NeuhouserCharles KooperbergLesley F TinkerNora FranceschiniTianXiao HuanThomas W WinklerAmy R BentleyW James GaudermanLuc HeerkensToshiko TanakaJeroen van RooijPatricia B MunroeHelen R WarrenTrudy G VoortmanHonglei ChenDabeeru C RaoDaniel LevyJiantao Manull nullPublished in: Hypertension (Dallas, Tex. : 1979) (2024)
We demonstrated gene-DASH diet score interaction effects on systolic BP in several loci. Studies with larger diverse populations are needed to validate our findings.
Keyphrases
- genome wide
- blood pressure
- dna methylation
- copy number
- hypertensive patients
- physical activity
- left ventricular
- weight loss
- heart failure
- heart rate
- type diabetes
- blood glucose
- genome wide association study
- transcription factor
- genome wide association
- metabolic syndrome
- case control
- adipose tissue
- skeletal muscle
- atrial fibrillation
- genome wide analysis