Blood-based biomarkers of neuronal and glial injury in active major neuropsychiatric systemic lupus erythematosus.

Ryan M Kammeyer Kimberly ChapmanAnna FurnissElena HsiehRobert FuhlbriggeEkemini A OgbuSusan BoackleJoAnn ZellKavita V NairTyler L BorkoJennifer C CooperJeffrey L BennettAmanda L Piquet

Published in: Lupus (2024)

Blood NfL and GFAP levels are elevated in persons with SLE with active major NPSLE compared to disease matched controls and may lower after immunotherapy initiation. Larger and longitudinal studies are needed to ascertain their utility in a clinical setting.

Keyphrases

systemic lupus erythematosus
disease activity
rheumatoid arthritis
case control
brain injury