Tumor characteristics associated with engraftment of patient-derived non-small cell lung cancer xenografts in immunocompromised mice.
Yungchang ChenRan ZhangLi WangArlene M CorreaApar PataerYi XuXiaoshan ZhangChenghui RenShuhong WuQing H MengJunya FujimotoVanessa B JensenMara B AntonoffWayne L HofstetterReza J MehranGeorge PisimisisDavid C RiceBoris SepesiAra A VaporciyanGarrett L WalshStephen G SwisherJack A RothJohn V HeymachBingliang FangPublished in: Cancer (2019)
The results of the current study indicate that the characteristics of cancer cells and the tumor immune microenvironment in primary tumors both can affect engraftment of a primary tumor sample.