Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus.
Beate RieblingerKonrad FischerAlexander KindBenedikt S SallerWiebke BaarsMarion SchusterLelia Wolf-van BuerckAndrea SchäfflerTatiana FlisikowskaMayuko KuromeValeri ZakhartchenkoBarbara KesslerKrzysztof FlisikowskiEckhard WolfJochen SeisslerReinhard SchwinzerAngelika SchniekePublished in: Xenotransplantation (2018)
Step-by-step placement enables highly expressed single-copy xenoprotective transgenes to be grouped at porcine ROSA26.