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SWATH-Proteomics of Ibrutinib's Action in Myeloid Leukemia Initiating Mutated G-CSFR Signaling.

Pankaj DwivediSomchai ChutipongtanateDavid E MuenchMohammad AzamHarry Leighton GrimesKenneth D Greis
Published in: Proteomics. Clinical applications (2020)
This robust dataset is available for further mining, hypothesis generation, and testing. A detailed understanding of the restructuring of the proteomics signaling cascades by ibrutinib in leukemia biology will provide new avenues to explore its use for other related malignancies.
Keyphrases
  • acute myeloid leukemia
  • bone marrow
  • mass spectrometry
  • chronic lymphocytic leukemia
  • label free
  • dendritic cells
  • immune response