Are we there yet with patent foramen ovale closure for secondary prevention in cryptogenic stroke? A systematic review and meta-analysis of randomized trials.
Pradyumna AgasthiKantha Ratnam KollaCharan YerasiSibghat TullahVenkata Siva PulivarthiBoshra LoukaReza ArsanjaniEric H YangFarouk MookadamF David FortuinPublished in: SAGE open medicine (2019)
This meta-analysis of randomized trials concludes that percutaneous patent foramen ovale closure is effective in recurrent stroke prevention especially in males and in those with a large shunt.