Autoantibodies to disease-related proteins in joints as novel biomarkers for the diagnosis of rheumatoid arthritis.
Erik LönnblomMonica Leu AgeliiOuti SareilaLei ChengBingze XuJohan ViljanenIngiäld HafströmMaria L E AnderssonGöran BergströmAnna-Karin Hultgård EkwallAnna RudinAlf KastbomChristopher SjöwallLennart Th JacobssonJan KihlbergInger GjertssonRikard HolmdahlPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
A multiplex immunoassay with peptides from disease-related proteins in joints was found to be useful for detection of specific autoantibodies in RA serum. Particularly, it had high discriminatory capacity for early seronegative RA.