Dual orexin receptor antagonists for the treatment of insomnia: systematic review and network meta-analysis.
Rebeka Bustamante RochaFernanda Ferreira BomtempoGabriela Borges NagerGiulia Isadora CenciJoão Paulo Motta TellesPublished in: Arquivos de neuro-psiquiatria (2023)
Our results suggest that DORAs are associated with greater efficacy when compared with placebo in the treatment of insomnia, a complex 24-hour sleep disorder. Additionally, dosing might play an important role in the management of chronic insomnia.
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