Genome-wide DNA methylation analysis of extreme phenotypes in the identification of novel epigenetic modifications in diabetic retinopathy.

Shaopeng YangXiao GuoWeijing ChengIshith SethGabriella BullochYifan ChenXianwen ShangZhuoting ZhuWenyong HuangMingguang He

Published in: Clinical epigenetics (2022)

Cg12869254 and cg04026387 hypermethylation may complement the known risk factors that contribute to the pathogenesis of DR and as novel biomarkers for disease prediction.

Keyphrases

dna methylation
diabetic retinopathy
genome wide
risk factors
optical coherence tomography
gene expression
copy number
climate change
editorial comment
bioinformatics analysis