Hepatoprotective potential of diosmin against hepatotoxic effect of isoniazid and rifampin in wistar rats.

Tarique AnwerMohammed N AlruwailiSaeed AlshahraniSaad S AlqahtaniAbdulmajeed JaliRayan A AhmedMohammad Firoz AlamSivakumar S Moni

Published in: Human & experimental toxicology (2023)

Results of the present study demonstrate hepatoprotective potential of diosmin against isoniazid-and rifampin-treated hepatotoxicity. Thus, we conclude that diosmin may be used along with anti-tubercular drugs (isoniazid and rifampin) in tuberculosis patients to overcome their hepatotoxic adverse effect.

Keyphrases

mycobacterium tuberculosis
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
drug induced
patient reported outcomes
adverse drug
hiv aids
human immunodeficiency virus
electronic health record