Evaluation of Der p 10 in a Cohort of European Children: Role of Molecular Diagnostics and Clinical Features.
Cristiana IndolfiGiulio DinardoAngela KlainAlessandra SalvatoriMarica EspositoViviana VelaFabio DecimoRiccardo CastagnoliMichele Miraglia Del GiudicePublished in: Journal of immunology research (2023)
The component-resolved diagnosis gave us a deeper understanding of patients' molecular sensitization profiles. Our study showed that a fair proportion of children sensitive to Der p 1 or Der p 2 are also sensitive to Der p 10. However, many patients sensitized to all three molecules had a high risk of asthma and anaphylaxis. Therefore, the assessment of Der p 10 sensitization should be considered in atopic patients with sensitization to Der p 1 and Der p 2 to avoid encountering possible adverse reactions after ingesting foods containing tropomyosins.