Hyperoxaluria Induces Endothelial Dysfunction in Preglomerular Arteries: Involvement of Oxidative Stress.

Javier Saenz-MedinaMercedes MuñozClaudia RodriguezCristina ContrerasAna SánchezMaría José CoronadoElvira RamilMartin Santos GonzalezJoaquín CarballidoDolores Prieto

Published in: Cells (2022)

The current data support that hyperoxaluria induces oxidative stress-mediated endothelial dysfunction and inflammatory response in renal preglomerular arteries which is promoted by the xanthine oxidase, Nox1 and Nox2 pathways.

Keyphrases

oxidative stress
inflammatory response
dna damage
reactive oxygen species
ischemia reperfusion injury
diabetic rats
induced apoptosis
electronic health record
lipopolysaccharide induced
uric acid
blood flow
lps induced
toll like receptor
big data
heat shock
endoplasmic reticulum stress
heat stress