Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A.

Jan AstermarkAnna OlssonPierre ChelleKinga TäckströmMaria WalgerMaria MagnussonAlfonso Iorio

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2021)

Our data support the use of population-based PK for patients on simoctocog alfa prophylaxis but also indicates differences, stressing the importance of the sampling scheme and monitoring actual FVIII levels achieved.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
big data
deep learning