Dihydrophenazine: A multifunctional new weapon that kills multidrug-resistant Acinetobacter baumannii and restores carbapenem and oxidative stress susceptibilities.
Norhan H MahdallyRiham A ElShiekhBathini ThisseraAshraf EltaherAya OsamaMaha MokhtarNoha M ElhosseinyMona T KashefSameh MagdeldinAli M El HalawanyMostafa E RatebAhmed S AttiaPublished in: Journal of applied microbiology (2024)
This work underscores the potential of DHP as a promising new agent with multifunctional roles as both a classical and non-conventional antimicrobial agent that is urgently needed.
Keyphrases
- acinetobacter baumannii
- multidrug resistant
- drug resistant
- oxidative stress
- drug delivery
- gram negative
- cancer therapy
- pseudomonas aeruginosa
- klebsiella pneumoniae
- staphylococcus aureus
- dna damage
- metal organic framework
- ischemia reperfusion injury
- diabetic rats
- escherichia coli
- risk assessment
- signaling pathway
- endoplasmic reticulum stress