Protamine dosing and its impact in cardiac surgery transfusion practice-A retrospective bi-institutional analysis.

Samhati MondalEzeldeen AbuelkasemRoumen VesselinovReney HendersonSeung ChoiAhmad MousaKhaled J ZazaKenichi A Tanaka

Published in: Transfusion (2024)

High protamine to heparin ratio may cause increased bleeding and transfusion in cardiac surgical patients. Protamine to heparin ratio of 0.8 or lower is sufficient to neutralize circulating heparin after weaning off cardiopulmonary bypass.

Keyphrases

cardiac surgery
venous thromboembolism
acute kidney injury
growth factor
healthcare
primary care
left ventricular
atrial fibrillation
sickle cell disease
mechanical ventilation
quality improvement
heart failure