The polymorphism G894 T of endothelial nitric oxide synthase (eNOS) gene is associated with susceptibility to essential hypertension (EH) in Morocco.

Sanaa NassereddineHind Hassani IdrissiRachida HabbalRhizlane AbouelfathFarah KorchMajda HarakaAdnane KarkarSellama Nadifi

Published in: BMC medical genetics (2018)

Our study suggests a strong association of G894 T eNOS polymorphism with susceptibility to EH in Morocco. Studies trying to identify contributing genes may be very useful and allow recognizing the vulnerable individuals and classifying patients in subgroups with definite genetic and pathogenic mechanisms to achieve better prevention and therapeutics.

Keyphrases

nitric oxide synthase
nitric oxide
genome wide
endothelial cells
end stage renal disease
blood pressure
newly diagnosed
copy number
chronic kidney disease
pi k akt
genome wide identification
small molecule
gene expression
cell proliferation
transcription factor
bioinformatics analysis