Single-cell landscape of intratumoral heterogeneity and tumor microenvironment remolding in pre-nodal metastases of breast cancer.

Kaidong LiuHuiming HanKai XiongSongmei ZhaiXiuqi YangXinmiao YuBo ChenMingyue LiuQi DongHongxue MengYunyan Gu

Published in: Journal of translational medicine (2024)

In summary, this study dissects the intratumoral heterogeneity and remodeling of the TME in pre-nodal metastases of breast cancer, providing novel insights into the mechanisms underlying breast cancer metastasis.

Keyphrases

single cell
rna seq
lymph node
neoadjuvant chemotherapy
high throughput
young adults