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Treatment with mycophenolate mofetil is associated with improved nailfold vasculature in systemic sclerosis.

Marie WildtKristofer AndréassonViggo HambergRoger HesselstrandDirk M Wuttge
Published in: Rheumatology (Oxford, England) (2023)
Nailfold capillary density improved over time in a substantial proportion of SSc patients. MMF treatment had a positive impact on the evolution of capillary density in these patients. SSc autoantibody phenotype may affect the capillary density development. The data support previous hypotheses that early immunosuppression may favourably affect vascular regeneration in SSc.
Keyphrases
  • systemic sclerosis
  • interstitial lung disease
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • stem cells
  • prognostic factors
  • machine learning
  • big data
  • artificial intelligence
  • patient reported