Treatment with mycophenolate mofetil is associated with improved nailfold vasculature in systemic sclerosis.
Marie WildtKristofer AndréassonViggo HambergRoger HesselstrandDirk M WuttgePublished in: Rheumatology (Oxford, England) (2023)
Nailfold capillary density improved over time in a substantial proportion of SSc patients. MMF treatment had a positive impact on the evolution of capillary density in these patients. SSc autoantibody phenotype may affect the capillary density development. The data support previous hypotheses that early immunosuppression may favourably affect vascular regeneration in SSc.