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A pharmacometrics model to define docetaxel target in early breast cancer.

Azucena AldazPaula S SchaiquevichJosé Manuel Aramendía
Published in: British journal of clinical pharmacology (2022)
We report for the first time a relation between docetaxel exposure and toxicity and recommend specific targets of drug exposure with implications for the clinical management of early breast cancer patients.
Keyphrases
  • early breast cancer
  • locally advanced
  • oxidative stress
  • squamous cell carcinoma
  • oxide nanoparticles