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CNVScope: Visually Exploring Copy Number Aberrations in Cancer Genomes.

James L T DalgleishYonghong WangJack ZhuPaul S Meltzer
Published in: Cancer informatics (2019)
The shiny application is readily available for use at http://cnvscope.nci.nih.gov/, and the package can be downloaded from CRAN (https://cran.r-project.org/package=CNVScope), where help pages and vignettes are located. A newer version is available on the GitHub site (https://github.com/jamesdalg/CNVScope/), which features an animated tutorial. The CNVScope package can be locally installed using instructions on the GitHub site for Windows and Macintosh systems. This CN analysis package also runs on a linux high-performance computing cluster, with options for multinode and multiprocessor analysis of CN variant data. The shiny application can be started using a single command (which will automatically install the public data package).
Keyphrases
  • copy number
  • mitochondrial dna
  • electronic health record
  • genome wide
  • lymph node metastasis
  • big data
  • mental health
  • quality improvement
  • squamous cell carcinoma
  • emergency department
  • machine learning