Pivotal role of orexin signaling in the posterior paraventricular nucleus of the thalamus during the stress-induced reinstatement of oxycodone-seeking behavior.
Jessica M IllenbergerFrancisco J Flores-RamirezGlenn PascasioMarissa FrancoBrandon MendonsaRémi Martin-FardonPublished in: Journal of psychopharmacology (Oxford, England) (2024)
The results indicate that OXR signaling in the pPVT is critical for stress-induced reinstatement of oxycodone seeking, further corroborating OXRs as treatment targets for opioid use disorder.