Integration of global metabolomics and lipidomics approaches reveals the molecular mechanisms and the potential biomarkers for postoperative recurrence in early-stage cholangiocarcinoma.
Sureerat PadthaisongJutarop PhetcharaburaninPoramate KlanritJia V LiNisana NamwatNarong KhuntikeoAttapol TitapunApiwat JarearnratArporn WangwiwatsinPanupong MahalapbutrWatcharin LoilomePublished in: Cancer & metabolism (2021)
Our study demonstrates the possible molecular mechanisms underlying CCA recurrence, and these may associate with the existence of CSCs. The metabolic change involved in the recurrence pathway might be used to determine biomarkers for predicting CCA recurrence.