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Molecular Mechanism of Polymyxin Resistance in Multidrug-Resistant Klebsiella pneumoniae and Escherichia coli Isolates from Henan Province, China: A Multicenter Study.

Wenjuan YanQi ZhangYingjie ZhuNan JingYouhua YuanYi ZhangSiying RenDongmei HuWenmin ZhaoXiaojuan ZhangCaiqin ShiMeiyun WangYi Li
Published in: Infection and drug resistance (2021)
The K. pneumoniae polymyxin resistance rate was slightly higher than that of E. coli and mcr-1 was more common in E. coli than in K. pneumoniae. Moreover, the insertion of ISkpn14 into mgrB may be the main contributor to polymyxin-resistance in K. pneumoniae in Henan.
Keyphrases
  • escherichia coli
  • klebsiella pneumoniae
  • multidrug resistant
  • gram negative
  • drug resistant
  • acinetobacter baumannii
  • biofilm formation
  • south africa