Clinical aspects of the three major genetic forms of long QT syndrome (LQT1, LQT2, LQT3).
Valentina KutyifaUsama A DaimeeScott McNittBronislava PolonskyCharles LowensteinKris CutterCoeli LopesWojciech ZarebaArthur J MossPublished in: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc (2018)
Risk factors and outcomes in LQTS patients varied by genotype. In all three genotypes, proband status and prolonged QTc were risk factors for cardiac events. Younger males and older females experienced increased risk in LQT1 and LQT2 only. Beta-blockers were most effective in reducing cardiac events in LQT1 and LQT2, with a potential benefit in LQT3 females.