Multi-Omic Candidate Screening for Markers of Severe Clinical Courses of COVID-19.

Alexander Dutsch Carsten UhligMatthias BockChristian Graesser Sven SchuchardtSteffen UhligHeribert SchunkertMichael JonerStefan HoldenriederKatharina Lechner

Published in: Journal of clinical medicine (2023)

Our novel prediction model identified biological and regulatory candidate networks preceding hyperinflammation and coagulopathy, with the most promising group being the proteins that explain changes in D-dimers. These biomarkers need validation. If causal, our work may help predict disease courses and guide personalized treatment for COVID-19.

Keyphrases

coronavirus disease
sars cov
respiratory syndrome coronavirus
transcription factor
early onset
drug induced