A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection.
Jiawei PeiYe TianWei YeJiangfan HanYamei DangTong ChengWei WangYipu ZhaoWeiliang YeShuyuan HuangfuYu LiFanglin ZhangYingfeng LeiAi-Rong QianPublished in: Cell & bioscience (2023)
Taken together, our results highlighted that transdermal administration of antiviral r/si-ORF7 was a promising therapeutic strategy for functional cure of VZV infection.