Predictors of clinical trajectories of patients with acutely decompensated cirrhosis. An external validation of the PREDICT study.
Enrico PompiliMaurizio BaldassarreGiorgio BedogniGiacomo ZaccheriniGiulia IannoneClara De VenutoDario PratelliFrancesco PalmeseMarco DomenicaliPaolo CaraceniPublished in: Liver international : official journal of the International Association for the Study of the Liver (2023)
The present study confirms that AD patients have three different clinical trajectories with different mortality rates. Besides the severity of cirrhosis, the association with C-reactive protein supports the predominant role of systemic inflammation in ACLF pathophysiology. Finally, HE is associated with the UDC phenotype highlighting the need for better management of this complication after discharge.