Kidney phosphate wasting predicts poor outcome in polycystic kidney disease.
Laixi XueFrank GeurtsEsther MeijerMartin H de BorstRon T GansevoortRobert ZietseEwout J HoornMahdi Salihnull nullPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2023)
Our study shows that in patients with ADPKD phosphate wasting is prevalent and associated with more rapid disease progression. Phosphate wasting may be a consequence of early proximal tubular dysfunction and insufficient suppression of PTH.