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Local heating-induced cutaneous vasodilation in reinnervated and noninnervated deep inferior epigastric perforator flaps.

Hansje P SmeeleLisa MartinSander M J van KuijkPieter R ZwanenburgRené R W J van der HulstStefania M H TuinderBérengère Fromy
Published in: Microsurgery (2023)
Our results suggest that free flap transfer causes longstanding impairment, yet not complete abolition, of both the sensory nerve-mediated and nitric oxide-dependent local heating-induced cutaneous vasodilatory systems. We found no statistical evidence that flap reinnervation improves the ability to raise skin blood flow in response to local heating.
Keyphrases
  • blood flow
  • breast reconstruction
  • nitric oxide
  • soft tissue
  • high glucose
  • oxidative stress
  • nitric oxide synthase
  • peripheral nerve