Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging.

Mariana BoroniAlessandra ZonariCarolina Reis de OliveiraKallie AlkatibEdgar Andres Ochoa CruzLear E BraceJuliana Lott de Carvalho

Published in: Clinical epigenetics (2020)

This highly accurate skin-specific DNAm age predictor constitutes a holistic tool that will be of great use in the analysis of human skin health status/molecular aging, as well as in the analysis of the potential of established and novel compounds to alter DNAm age.

Keyphrases

high throughput
soft tissue
high resolution
wound healing
machine learning
nk cells
small molecule
deep learning
risk assessment
mass spectrometry
data analysis