Novel imaging biomarkers predict outcomes in stage III unresectable non-small cell lung cancer treated with chemoradiation and durvalumab.
Khalid JaziehMohammadhadi KhorramiAnas SaadMohamed GadAmit GuptaPradnya PatilVidya Sankar ViswanathanPrabhakar RajiahCharles J NockMichael GilkeyPingfu FuNathan A PennellAnant MadabhushiPublished in: Journal for immunotherapy of cancer (2022)
Tumor radiomics of pretreatment CT images from patients with stage III unresectable NSCLC were prognostic of PFS and OS to CRT followed by durvalumab IO and CRT alone.
Keyphrases
- locally advanced
- rectal cancer
- cardiac resynchronization therapy
- contrast enhanced
- squamous cell carcinoma
- liver metastases
- small cell lung cancer
- radiation therapy
- high resolution
- deep learning
- computed tomography
- lymph node metastasis
- image quality
- convolutional neural network
- heart failure
- advanced non small cell lung cancer
- left ventricular
- dual energy
- magnetic resonance imaging
- optical coherence tomography
- magnetic resonance
- positron emission tomography
- newly diagnosed
- type diabetes
- metabolic syndrome
- fluorescence imaging
- skeletal muscle
- photodynamic therapy
- insulin resistance
- pet ct