Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Shiyi TianJue WangRen GaoJing WangWeiyun ZhuPublished in: Journal of animal science and biotechnology (2022)
These results suggested that GOS enhanced the gut function, reduced the ROS production and pro-apoptotic factors gene expression, and activated the AMPK signaling pathway in LPS-challenged piglets.
Keyphrases
- early life
- oxidative stress
- anti inflammatory
- gene expression
- cell death
- signaling pathway
- inflammatory response
- dna damage
- induced apoptosis
- dna methylation
- pi k akt
- toll like receptor
- diabetic rats
- ischemia reperfusion injury
- lps induced
- skeletal muscle
- epithelial mesenchymal transition
- reactive oxygen species
- mouse model
- protein kinase
- immune response
- cell proliferation
- heat shock