External validation of the GRACE risk score and the risk-treatment paradox in patients with acute coronary syndrome.
Niels M R van der SangenJaouad AzzahhafiDean R P P Chan Pin YinJoyce PeperSenna RayhiRonald J WalhoutR Melvyn Tjon Joe GinDeborah M NicastiaJorina LangerveldGeorgios J VlachojannisRutger J van BommelYolande AppelmanJosé P S HenriquesJurrien M Ten BergWouter J KikkertPublished in: Open heart (2022)
The GRACE risk score identified patients at higher risk for in-hospital and 1-year mortality, but overestimated absolute risk levels in contemporary patients. Optimal guideline-recommended care was associated with lower mortality in intermediate-risk and high-risk patients, but was less likely to be delivered with increasing mortality risk.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- healthcare
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- palliative care
- cardiovascular events
- emergency department
- risk factors
- type diabetes
- cardiovascular disease
- chronic pain
- electronic health record
- quality improvement
- acute care
- affordable care act